Factors influencing postoperative morbidity and mortality in patients treated with bleomycin

Paul L. Goldiner, Graziano C. Carlon, Esteban Cvitkovic, Olga Schweizer, William S. Howland

Research output: Contribution to journalArticlepeer-review

173 Scopus citations

Abstract

Patients treated with bleomycin are at risk of developing the acute adult respiratory distress syndrome postoperatively. In a prospective study of 12 patients who had received bleomycin preoperatively and were under-going removal of retroperitoneal lymph nodes or pulmonary metastases several preventive factors were established. These were the use of low concentrations of inspired oxygen during operation and in the immediate postoperative period, careful monitoring of fluid replacement, and restriction of crystalloids in favour of colloids.

Original languageEnglish
Pages (from-to)1664-1667
Number of pages4
JournalThe BMJ
Volume1
Issue number6128
DOIs
StatePublished - 24 Jun 1978
Externally publishedYes

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