Factors associated with complications in total laryngectomy without microvascular reconstruction

Samuel N. Helman, Jason A. Brant, Sameep K. Kadakia, Jason G. Newman, Steven B. Cannady, Raymond L. Chai

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Background: There is little population-level data evaluating risk factors for postoperative complications after total laryngectomy. Methods: We conducted a retrospective review of the American College of Surgeons National Quality Improvement Program identifying patients who underwent total laryngectomy as a primary procedure from 2005 to 2014. Multivariate analysis was performed to identify variables that were independently associated with overall and major complications. Results: Eight hundred seventy-one cases met inclusion criteria. Three hundred twenty-eight patients (37.7%) had complications, with operative time (hours; P <.0001), class III (P <.001) wound status, and patient age (decade; P =.003) associated with overall complications. Two hundred one patients had major complications that were associated with steroid use (P =.01) and class III (P =.0083) wound classification. Preoperative hematocrit was correlated with a reduction of all and major complications on multivariate analysis (P <.0001 and P =.036). Conclusion: Identifying and optimizing risk factors may improve outcomes in total laryngectomy.

Original languageEnglish
Pages (from-to)2409-2415
Number of pages7
JournalHead and Neck
Issue number11
StatePublished - Nov 2018


  • National Surgical Quality Improvement Program
  • major complications
  • postoperative complications
  • total laryngectomy


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