Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

Thomas J. Flotte; Virgil A. Hatcher; Alvin E. Friedman Kien

doi:10.1001/archderm.1984.01650380040007

Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

Thomas J. Flotte, Virgil A. Hatcher, Alvin E. Friedman Kien

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27 Scopus citations

Abstract

This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

Original language	English
Pages (from-to)	180-182
Number of pages	3
Journal	Archives of Dermatology
Volume	120
Issue number	2
DOIs	https://doi.org/10.1001/archderm.1984.01650380040007
State	Published - Feb 1984
Externally published	Yes

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title = "Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men",

abstract = "This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.",

author = "Flotte, {Thomas J.} and Hatcher, {Virgil A.} and {Friedman Kien}, {Alvin E.}",

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AB - This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.

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Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men

Abstract

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