FA iPS: Correction or reprogramming first?

Eirini P. Papapetrou

doi:10.1182/blood-2012-04-417246

FA iPS: Correction or reprogramming first?

Eirini P. Papapetrou

Research output: Contribution to journal › Comment/debate

1 Scopus citations

Abstract

In this issue of Blood, Müller et al show that Fanconi anemia (FA) cells are resistant, but not completely refractory, to reprogramming into induced pluripotent stem (iPS) cells. Genetic complementation before reprogramming restores DNA repair, rescues reprogramming, and yields iPS cells less likely to contain genetic alterations.

Original language	English
Pages (from-to)	5341-5342
Number of pages	2
Journal	Blood
Volume	119
Issue number	23
DOIs	https://doi.org/10.1182/blood-2012-04-417246
State	Published - 7 Jun 2012
Externally published	Yes

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10.1182/blood-2012-04-417246

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title = "FA iPS: Correction or reprogramming first?",

abstract = "In this issue of Blood, M{\"u}ller et al show that Fanconi anemia (FA) cells are resistant, but not completely refractory, to reprogramming into induced pluripotent stem (iPS) cells. Genetic complementation before reprogramming restores DNA repair, rescues reprogramming, and yields iPS cells less likely to contain genetic alterations.",

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AB - In this issue of Blood, Müller et al show that Fanconi anemia (FA) cells are resistant, but not completely refractory, to reprogramming into induced pluripotent stem (iPS) cells. Genetic complementation before reprogramming restores DNA repair, rescues reprogramming, and yields iPS cells less likely to contain genetic alterations.

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DO - 10.1182/blood-2012-04-417246

M3 - Comment/debate

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ER -

FA iPS: Correction or reprogramming first?

Abstract

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