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EZH2 is essential for glioblastoma cancer stem cell maintenance
Mario Luca Suvà
, Nicolò Riggi
, Michalina Janiszewska
, Ivan Radovanovic
, Paolo Provero
, Jean Christophe Stehle
, Karine Baumer
, Marie Aude Le Bitoux
, Denis Marino
, Luisa Cironi
, Victor E. Marquez
, Virginie Clément
, Ivan Stamenkovic
Research output
:
Contribution to journal
›
Article
›
peer-review
423
Scopus citations
Overview
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Keyphrases
Enhancer of Zeste Homolog 2 (EZH2)
100%
Stem Cell Maintenance
100%
Glioma Stem Cells
100%
Glioblastoma multiforme
77%
C-Myc
33%
Breast Cancer
22%
Short Hairpin RNA (shRNA)
22%
Cancer Stem Cells
22%
3-deazaneplanocin A
22%
Malignancy
11%
Cell Differentiation
11%
Pharmacologic
11%
Overexpression
11%
Novel Mechanism
11%
DNA Repair
11%
Prostate Cancer
11%
Cell Tumor
11%
Tumor Development
11%
Stem Cell Self-renewal
11%
RNA-based
11%
Transcriptional Regulation
11%
Polycomb Group (PcG) Proteins
11%
Chromatin Immunoprecipitation (ChIP)
11%
New Drug Targets
11%
Genome-wide Expression
11%
Direct Target
11%
Cell Cycle Control
11%
Tissue Stem Cells
11%
Tumor-initiating
11%
Hydrolase Inhibitors
11%
S-adenosylhomocysteine Hydrolase
11%
Pharmacology, Toxicology and Pharmaceutical Science
Malignant Neoplasm
100%
Glioblastoma
100%
Transcription Factor EZH2
100%
Neoplasm
22%
Short Hairpin RNA
22%
3-Deazaneplanocin A
22%
Breast Cancer
11%
Prostate Cancer
11%
Chromatin Immunoprecipitation
11%
S Adenosylhomocysteine
11%
Polycomb Group Protein
11%
Adenosylhomocysteinase
11%
Hydrolase Inhibitor
11%
Biochemistry, Genetics and Molecular Biology
Cancer Stem Cell
100%
Transcription Factor EZH2
100%
Oncogene C Myc
33%
Downregulation
22%
Small Hairpin RNA
22%
3-Deazaneplanocin A
22%
Small Interfering RNA
22%
Transcription
11%
Stem Cell
11%
Cell Cycle Regulation
11%
DNA Repair
11%
Cellular Differentiation
11%
Stem Cell Self-Renewal
11%
Hydrolase
11%
Polycomb-Group Proteins
11%
Chromatin Immunoprecipitation
11%
Expression Analysis
11%
S-Adenosyl-L-Homocysteine
11%
Immunology and Microbiology
Cancer Stem Cell
100%
Transcription Factor EZH2
100%
Oncogene C Myc
33%
Downregulation
22%
Ribonucleic Acid
22%
Stem Cell
11%
Cell Differentiation
11%
DNA Repair
11%
Stem Cell Self-Renewal
11%
Cell Cycle Regulation
11%
Chromatin Immunoprecipitation
11%
Expression Analysis
11%
Polycomb-Group Proteins
11%
In Vitro
11%