Extraordinary hyperbilirubinemia in a neonate with idiopathic hypertrophic pyloric stenosis

Michael A. Bleicher, Mark A. Reiner, Susan A. Rapaport, Norman S. Track

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

This case describes an extraordinarily elevated total bilirubin level that reverted to normal 9 1/2 wk after Fredet-Ramstedt pyloromyotomy. Although the etiology of jaundice occurring in patients with IHPS remains uncertain, theories implicating inhibition of the glucuronyl transferase system have been proposed. Infants with IHPS have a documented hypergastrinemia. An hypothesis is offered, illustrated by this case, to explain the inhibition of the glucuronyl transferase system with resultant hyperbilirubinemia by the hypergastrinemia of idiopathic hypertrophic pyloric stenosis.

Original languageEnglish
Pages (from-to)527-529
Number of pages3
JournalJournal of Pediatric Surgery
Volume14
Issue number5
DOIs
StatePublished - Oct 1979

Keywords

  • Hypertrophic pyloric stenosis

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