Extracorporeal Therapies in Acute Intoxication and Poisoning

Nikolas Harbord; James Frank Winchester; Elliot Charen; Naitik Sheth; Arjun Bhansali

doi:10.1016/B978-0-323-44942-7.00099-6

Extracorporeal Therapies in Acute Intoxication and Poisoning

Nikolas Harbord, James Frank Winchester, Elliot Charen, Naitik Sheth, Arjun Bhansali

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

The chapter provides an overview of the management of the poisoned patient and introduces extracorporeal therapies to aid in detoxification. Indications for the use of hemodialysis, hemofiltration, and hemoperfusion are reviewed, and the principles underlying drug removal with each modality are described. Additional consideration is given to addition of chelating agents to augment clearance of metals, such as aluminum and iron. Clinical presentation, diagnosis, and therapeutic approach including extracorporeal treatment are described in detail for specific intoxicants: lithium, methanol, ethylene glycol, and salicylates. Comprehensive tables are included, containing drugs and intoxicants removed with extracorporeal therapy.

Original language	English
Title of host publication	Critical Care Nephrology
Subtitle of host publication	Third Edition
Publisher	Elsevier Inc.
Pages	588-594.e1
ISBN (Electronic)	9780323449427
ISBN (Print)	9780323449427
DOIs	https://doi.org/10.1016/B978-0-323-44942-7.00099-6
State	Published - 2019

Keywords

Chelation
Ethylene glycol
Hemodialysis
Hemofiltration
Hemoperfusion
Intoxication
Lithium
Methanol
Poisoning
Salicylates
Theophylline

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10.1016/B978-0-323-44942-7.00099-6

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title = "Extracorporeal Therapies in Acute Intoxication and Poisoning",

abstract = "The chapter provides an overview of the management of the poisoned patient and introduces extracorporeal therapies to aid in detoxification. Indications for the use of hemodialysis, hemofiltration, and hemoperfusion are reviewed, and the principles underlying drug removal with each modality are described. Additional consideration is given to addition of chelating agents to augment clearance of metals, such as aluminum and iron. Clinical presentation, diagnosis, and therapeutic approach including extracorporeal treatment are described in detail for specific intoxicants: lithium, methanol, ethylene glycol, and salicylates. Comprehensive tables are included, containing drugs and intoxicants removed with extracorporeal therapy.",

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AU - Harbord, Nikolas

AU - Winchester, James Frank

AU - Charen, Elliot

AU - Sheth, Naitik

AU - Bhansali, Arjun

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AB - The chapter provides an overview of the management of the poisoned patient and introduces extracorporeal therapies to aid in detoxification. Indications for the use of hemodialysis, hemofiltration, and hemoperfusion are reviewed, and the principles underlying drug removal with each modality are described. Additional consideration is given to addition of chelating agents to augment clearance of metals, such as aluminum and iron. Clinical presentation, diagnosis, and therapeutic approach including extracorporeal treatment are described in detail for specific intoxicants: lithium, methanol, ethylene glycol, and salicylates. Comprehensive tables are included, containing drugs and intoxicants removed with extracorporeal therapy.

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KW - Ethylene glycol

KW - Hemodialysis

KW - Hemofiltration

KW - Hemoperfusion

KW - Intoxication

KW - Lithium

KW - Methanol

KW - Poisoning

KW - Salicylates

KW - Theophylline

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PB - Elsevier Inc.

ER -

Extracorporeal Therapies in Acute Intoxication and Poisoning

Abstract

Keywords

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