TY - JOUR
T1 - Expression of vertebrate homologs of the Drosophila msh gene during early craniofacial development
AU - Ramirez, Francesco
AU - Solursh, Michael
N1 - Funding Information:
I would like to thank the other two organizers of the Symposium on the Development and Evolution of the Vertebrate Head, Brian Hall and Michael Solursh. I greatly appreciate Sharon Gerhing and John Armstrong sharing their preliminary data with me. Shelley Dudley provided excellent technical assistance and Shirley Lord provided valuable help in typing the manuscript. RML is the recipient of an NSERC of Canada URF scholarship. Funding for this work was provided by MRC of Canada, grant MT-10579. Funding from an NSF grant to RML, M. Solursh and B. K. Hall in support of the symposium in which this paper was presented is gratefully acknowledged.
PY - 1993
Y1 - 1993
N2 - It has become clear that many gene products containing the homeodomain, a helix-turn-helix DNA motif, are involved in establishing the initial pattern of differentiation during development. The msh family of homeobox containing genes is just being characterized in vertebrate embryos where it is widely expressed during craniofacial development msh transcripts accumulate in the dorsal neural tube, presumptive neural crest, and many tissues in the craniofacial region during a period when tissue patterning is occurring, but not after cytodifferentiation. Based on these observations, it is likely that this group of homeobox containing genes is involved in the development and evolution of the craniofacial region.
AB - It has become clear that many gene products containing the homeodomain, a helix-turn-helix DNA motif, are involved in establishing the initial pattern of differentiation during development. The msh family of homeobox containing genes is just being characterized in vertebrate embryos where it is widely expressed during craniofacial development msh transcripts accumulate in the dorsal neural tube, presumptive neural crest, and many tissues in the craniofacial region during a period when tissue patterning is occurring, but not after cytodifferentiation. Based on these observations, it is likely that this group of homeobox containing genes is involved in the development and evolution of the craniofacial region.
UR - http://www.scopus.com/inward/record.url?scp=9544242466&partnerID=8YFLogxK
U2 - 10.1093/icb/33.4.457
DO - 10.1093/icb/33.4.457
M3 - Article
AN - SCOPUS:9544242466
SN - 1540-7063
VL - 33
SP - 457
EP - 461
JO - Integrative and Comparative Biology
JF - Integrative and Comparative Biology
IS - 4
ER -