Expression of Toll-like receptors in the kidney: Their potential role beyond infection

B. Schröppel, J. C. He

Research output: Contribution to journalComment/debate

22 Scopus citations

Abstract

Toll-like receptors (TLRs) recognize both exogenous microbial components and endogenous molecules to promote immune activation. Both immune and nonimmune renal cells expressTLRs, which are involved in the pathogenesis of a number of kidney diseases, including pyelonephritis, Leptospira nephritis, immune-complex glomerulonephritis, ischemic/reperfusion injury, and rejection of kidney transplant.

Original languageEnglish
Pages (from-to)785-787
Number of pages3
JournalKidney International
Volume69
Issue number5
DOIs
StatePublished - Mar 2006

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