Exploiting dendritic cells for active immunotherapy of cancer and chronic infections

David W. O'Neill; Nina Bhardwaj

doi:10.1007/s12033-007-0020-6

Exploiting dendritic cells for active immunotherapy of cancer and chronic infections

David W. O'Neill, Nina Bhardwaj

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

Dendritic cells (DCs) are important antigen-presenting cells (APCs) that can prime naive T cells and control adaptive immune responses with respect to magnitude, memory and self-tolerance. Understanding the biology of these cells is central to the development of new generation immunotherapies for cancer and chronic infections. This review presents a brief overview of DC biology and of the preparation and use of DC-based vaccines.

Original language	English
Pages (from-to)	131-141
Number of pages	11
Journal	Molecular Biotechnology
Volume	36
Issue number	2
DOIs	https://doi.org/10.1007/s12033-007-0020-6
State	Published - Jun 2007
Externally published	Yes

Keywords

Antigen presenting
Cancer
Dendritic
Vaccine

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10.1007/s12033-007-0020-6

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KW - Vaccine

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Exploiting dendritic cells for active immunotherapy of cancer and chronic infections

Abstract

Keywords

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