Experimental management by nonoperative adrenergic stimulation of simulated common duct stones

Herbert Dardik; Thomas Beneventano; Richard Rosen; Marvin L. Gliedman; Clarence J. Schein

doi:10.1007/BF02235207

Experimental management by nonoperative adrenergic stimulation of simulated common duct stones

Herbert Dardik, Thomas Beneventano, Richard Rosen, Marvin L. Gliedman, Clarence J. Schein

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The effects of β-receptor stimulation by isoproterenol on ampullary flow and passage of intracholedochal foreign bodies were evaluated in dogs. Flow rates for saline across the ampulla were unchanged by β stimulation except for the earlier appearance of flow in association with a decrease in sphincteric resistance. The mean irrigation pressures required for the passage of a foreign body into the duodenum decreased by 46% from control values when isoproterenol was infused. Stimulation of β receptors may thus serve as a valuable adjunct in the management of patients with retained choledochal calculi by decreasing ampullary resistance. The ineffectiveness and hazards of previously utilized agents is discussed.

Original language	English
Pages (from-to)	321-326
Number of pages	6
Journal	Digestive Diseases and Sciences
Volume	16
Issue number	4
DOIs	https://doi.org/10.1007/BF02235207
State	Published - Apr 1971
Externally published	Yes

Access to Document

10.1007/BF02235207

Cite this

@article{f7b8a224fa4d4d9d8c0444d981e7e274,

title = "Experimental management by nonoperative adrenergic stimulation of simulated common duct stones",

abstract = "The effects of β-receptor stimulation by isoproterenol on ampullary flow and passage of intracholedochal foreign bodies were evaluated in dogs. Flow rates for saline across the ampulla were unchanged by β stimulation except for the earlier appearance of flow in association with a decrease in sphincteric resistance. The mean irrigation pressures required for the passage of a foreign body into the duodenum decreased by 46% from control values when isoproterenol was infused. Stimulation of β receptors may thus serve as a valuable adjunct in the management of patients with retained choledochal calculi by decreasing ampullary resistance. The ineffectiveness and hazards of previously utilized agents is discussed.",

author = "Herbert Dardik and Thomas Beneventano and Richard Rosen and Gliedman, {Marvin L.} and Schein, {Clarence J.}",

year = "1971",

month = apr,

doi = "10.1007/BF02235207",

language = "English",

volume = "16",

pages = "321--326",

journal = "Digestive Diseases and Sciences",

issn = "0002-9211",

publisher = "Springer",

number = "4",

}

TY - JOUR

T1 - Experimental management by nonoperative adrenergic stimulation of simulated common duct stones

AU - Dardik, Herbert

AU - Beneventano, Thomas

AU - Rosen, Richard

AU - Gliedman, Marvin L.

AU - Schein, Clarence J.

PY - 1971/4

Y1 - 1971/4

N2 - The effects of β-receptor stimulation by isoproterenol on ampullary flow and passage of intracholedochal foreign bodies were evaluated in dogs. Flow rates for saline across the ampulla were unchanged by β stimulation except for the earlier appearance of flow in association with a decrease in sphincteric resistance. The mean irrigation pressures required for the passage of a foreign body into the duodenum decreased by 46% from control values when isoproterenol was infused. Stimulation of β receptors may thus serve as a valuable adjunct in the management of patients with retained choledochal calculi by decreasing ampullary resistance. The ineffectiveness and hazards of previously utilized agents is discussed.

AB - The effects of β-receptor stimulation by isoproterenol on ampullary flow and passage of intracholedochal foreign bodies were evaluated in dogs. Flow rates for saline across the ampulla were unchanged by β stimulation except for the earlier appearance of flow in association with a decrease in sphincteric resistance. The mean irrigation pressures required for the passage of a foreign body into the duodenum decreased by 46% from control values when isoproterenol was infused. Stimulation of β receptors may thus serve as a valuable adjunct in the management of patients with retained choledochal calculi by decreasing ampullary resistance. The ineffectiveness and hazards of previously utilized agents is discussed.

UR - http://www.scopus.com/inward/record.url?scp=0015042147&partnerID=8YFLogxK

U2 - 10.1007/BF02235207

DO - 10.1007/BF02235207

M3 - Article

C2 - 5554837

AN - SCOPUS:0015042147

SN - 0002-9211

VL - 16

SP - 321

EP - 326

JO - Digestive Diseases and Sciences

JF - Digestive Diseases and Sciences

IS - 4

ER -

Experimental management by nonoperative adrenergic stimulation of simulated common duct stones

Abstract

Access to Document

Fingerprint

Cite this