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Expanding PROTACtable genome universe of E3 ligases
Yuan Liu
, Jingwen Yang
, Tianlu Wang
, Mei Luo
, Yamei Chen
, Chengxuan Chen
,
Ze’ev Ronai
, Yubin Zhou
, Eytan Ruppin
, Leng Han
Research output
:
Contribution to journal
›
Article
›
peer-review
117
Scopus citations
Overview
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Keyphrases
E3 Ligase
100%
Proteolysis Targeting chimera (PROTAC)
50%
Targeted Protein Degradation
50%
Protein-protein Interaction
37%
Expression Pattern
25%
Ligandability
25%
In Cancer
12%
Therapeutic Potential
12%
Cellular Proteins
12%
Ubiquitin-proteasome System
12%
Small Molecules
12%
Human Genome
12%
Web Portal
12%
Protein-protein Interface
12%
Degradation Process
12%
Degradation Activity
12%
Cellular Location
12%
Confidence Score
12%
Large-scale Dataset
12%
Interaction Structure
12%
Flexible Web
12%
Biochemistry, Genetics and Molecular Biology
Ubiquitin Ligase
100%
Protein Catabolism
50%
Protein-Protein Interaction
37%
Proteolysis
25%
Small Molecule
12%
Proteasome
12%
Ubiquitin
12%
Human Genome
12%
Pharmacology, Toxicology and Pharmaceutical Science
Ligase
100%
Malignant Neoplasm
12%
Proteasome
12%
Ubiquitin
12%