Excretion of a tryptophan metabolite in rheumatoid arthritis

Harry Spiera

doi:10.1002/art.1780060407

Excretion of a tryptophan metabolite in rheumatoid arthritis

Harry Spiera

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The excretion of 3 hydroxy anthranilic acid, a metabolite of trytophan, was studied in a group of patients with rheumatoid arthritis, the other connective tissue diseases, and hospital controls. Ten of 26 patients with rheumatoid arthritis, 3 of 18 with the collagen diseases, and only 1 of 26 hospital controls excreted more than 500 μg. per 24 hours. The quantity excreted did not correlate with any other clinical or laboratory parameter studied. The cause and significance of the increased excretion are unknown.

Original language	English
Pages (from-to)	364-371
Number of pages	8
Journal	Arthritis and Rheumatology
Volume	6
Issue number	4
DOIs	https://doi.org/10.1002/art.1780060407
State	Published - Aug 1963
Externally published	Yes

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title = "Excretion of a tryptophan metabolite in rheumatoid arthritis",

abstract = "The excretion of 3 hydroxy anthranilic acid, a metabolite of trytophan, was studied in a group of patients with rheumatoid arthritis, the other connective tissue diseases, and hospital controls. Ten of 26 patients with rheumatoid arthritis, 3 of 18 with the collagen diseases, and only 1 of 26 hospital controls excreted more than 500 μg. per 24 hours. The quantity excreted did not correlate with any other clinical or laboratory parameter studied. The cause and significance of the increased excretion are unknown.",

author = "Harry Spiera",

year = "1963",

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N2 - The excretion of 3 hydroxy anthranilic acid, a metabolite of trytophan, was studied in a group of patients with rheumatoid arthritis, the other connective tissue diseases, and hospital controls. Ten of 26 patients with rheumatoid arthritis, 3 of 18 with the collagen diseases, and only 1 of 26 hospital controls excreted more than 500 μg. per 24 hours. The quantity excreted did not correlate with any other clinical or laboratory parameter studied. The cause and significance of the increased excretion are unknown.

AB - The excretion of 3 hydroxy anthranilic acid, a metabolite of trytophan, was studied in a group of patients with rheumatoid arthritis, the other connective tissue diseases, and hospital controls. Ten of 26 patients with rheumatoid arthritis, 3 of 18 with the collagen diseases, and only 1 of 26 hospital controls excreted more than 500 μg. per 24 hours. The quantity excreted did not correlate with any other clinical or laboratory parameter studied. The cause and significance of the increased excretion are unknown.

UR - https://www.scopus.com/pages/publications/78651152674

U2 - 10.1002/art.1780060407

DO - 10.1002/art.1780060407

M3 - Article

C2 - 14052857

AN - SCOPUS:78651152674

SN - 0004-3591

VL - 6

SP - 364

EP - 371

JO - Arthritis and Rheumatology

JF - Arthritis and Rheumatology

IS - 4

ER -

Excretion of a tryptophan metabolite in rheumatoid arthritis

Abstract

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