Evidence of Validity of the Autism Mental Status Examination (AMSE) in a Brazilian Sample

Marlene Pereira Galdino, Luiz Fernando Longuim Pegoraro, Laura Olalla Saad, David Grodberg, Eloisa Helena Rubello Valler Celeri

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8 Scopus citations


This study investigated the psychometric properties of the Autism Mental Status Examination (AMSE) in a Brazilian sample of children and adolescents with autism spectrum disorder (ASD). A sample of 260 children and adolescents, comprising 56 (21.5%) females and 204 (78.5%) males, was assessed. The participants were submitted to both the childhood autism rating scale (CARS-BR) and the AMSE. The CARS-BR was used to estimate ASD severity and the cutoff point on the AMSE. Spearman’s correlation test was employed to determine the correlation between the AMSE and CARS-BR scales. The cutoff values were calculated using the ROC (receiver operating characteristic) curve, identifying the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). The homogeneity of the items of the AMSE was determined using Cronbach´s alpha. The AMSE exhibited good internal consistency (0.74), sensitivity (0.91) and specificity (0.98); and high correlation with the CARS-BR (ρ = 0.91, p < 0.01). Preliminary results showed that the AMSE is a tool with good psychometric properties for ASD screening.

Original languageEnglish
Pages (from-to)2320-2325
Number of pages6
JournalJournal of Autism and Developmental Disorders
Issue number7
StatePublished - 1 Jul 2020
Externally publishedYes


  • Autism Mental Status Examination
  • Autism spectrum disorder
  • Observational evaluation
  • Standardized psychiatric interview


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