Evidence for distinct lymphocytic and monocytic populations in a patient with terminal transferase-positive acute leukemia

R. Mertelsmann, B. Koziner, P. Ralph, D. Filippa, S. McKenzie, Z. A. Arlin, T. S. Gee, M. A. Moore, B. D. Clarkson

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

Two distinct cell populations with lymphoblastic and monocytic characteristics were separated and characterized by multiple cell markers in a patient with terminal transferase-positive acute leukemia. The clinical course and sequential cell marker studies were consistent with the interpretation of a defect at the level of a common stem cell giving rise to a terminal transferase-positive lymphoblastic cell population at diagnosis and, following initial therapy, a terminal transferase-negative monocytic population.

Original languageEnglish
Pages (from-to)1051-1056
Number of pages6
JournalUnknown Journal
Volume51
Issue number6
DOIs
StatePublished - 1978
Externally publishedYes

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