Evaluation of the intermittent exotropia questionnaire using rasch analysis

David A. Leske, Jonathan M. Holmes, B. Michele Melia, Aaron Miller, Jorie Jackson, Donny Suh, Susan Hayes, Stephen Glaser, Monica Pacheco, Laura Graham, Evelyn Paysse, Kimberly Yen, Mohamed Hussein, Paul Steinkuller, David Coats, Lingkun Kong, Sean Donahue, David Morrison, Lori Ann Kehler, Robert EstesLisa Fraine, David Petersen, J. McMurtrey, Nicholas Sala, Jeanine Romeo, Earl Crouch, Gaylord Ventura, Brian Mohney, Tomohiko Yamada, Sarah Hatt, Rebecca Nielsen, Laura Liebermann, Rosanne Superstein, Caroline Belanger, Nicole Fallaha, Maryse Thibeault, Benjamin Ticho, Alexander Khammar, Megan Allen, Deborah Clausius, Darren Hoover, Pamela Huston, Laura Enyedi, David Wallace, Tammy Yanovitch, Sarah Jones, David Silbert, Noelle Matta, Richard Weaver, Eric Hein, Lori Cooke, Scott Lambert, Phoebe Lenhart, Amy Hutchinson, Judy Brower, Robert Rutstein, Wendy Marsh-Tootle, Katherine Weise, Marcela Frazier, Ross Roegner, Susan Cotter, Angela Chen, Carmen Barnhardt, Kristine Huang, Paula Handford, Reena Patel, Catherine Heyman, Raymond Chu, Lernik Mesropian, Susan Parker, Susanna Tamkins, Todd Goldblum, Kenneth Adams, Angela Alfaro, Christie Morse, Maynard Wheeler, Melanie Christian, C. Gail Summers, Jill Anderson, Erick Bothun, Inge De Becker, Sarah Downes, Ann Holleschau, Nausheen Khuddus, Tammy Price, Bahram Rahmani, Hawke Yoon, Yana Kiesau, Aaliyah Hamidullah, Joan Roberts, Heather Klem, Brian Arthur, Lesley Macsween, William Astle, Kenneth Romanchuk, Emi Sanders, Robert Duckman, Marilyn Vricella, Sara Meeder, Patricia Davis, Indre Rudaitis, Mae Peterseim, Ronald Teed, Carol Bradham, Mary Louise Collins, Allison Jensen, Maureen Flanagan, Daniel Karr, Allison Summers, Ann Stout, Paula Rauch, Yi Pang, Anesu Mvududu, Michael Bartiss, Tennille McGaw, Faruk Ogre, Beth Colon, Mitchell Scheiman, Karen Pollack, Jean Ramsey, Stephen Christiansen, Elise Harb, Vanessa Vazquez, Ruth E. Manny, Karen D. Fern, Catherine McDaniel, Heather Anderson, Joan Do, Adriana Grigorian, Rebecca Dent, Ilana Friedman, Evelyn Koestenblatt, G. Robert La Roche, Stephen Van Iderstine, Michael X. Repka, Hee Jung Park, Xiaonong Liu, Alex Christoff, David Tien, Samantha Garner, Richard London, Jayne Silver, Don Lyon, Tawna Roberts, Vivian Wong, Kristy Dunlap, Matthew Gearinger, Peter Macdowell, Mary O'Hara, Nandini Gandhi, Elias Traboulsi, Paul Rychwalski, Susan Crowe, Edward Cheeseman, Michelle Bass, Jeffery Colburn, Eileen Dittman, Susannah Longmuir, Wanda Ottar Pfeifer, Daniel Neely, Michele Whitaker, Marjean Kulp, Andrew Toole, Tamara Oechslin, Freda Dallas, Nancy Stevens, Yasmin Bradfield, Barbara Soderling, Mitchell Strominger, Shelley Klein, Erin Herlihy, Jennifer Brady, Gregory Ostrow, Laura Kirkeby, Tamiesha Frempong, Dipali Dave, Stacy Pineles, Marianne Esguerra, Sergul Erzurum, Diana McOwen, Brian Forbes, Gil Binenbaum, Karen Karp, Tara Cronin, Cheryl Capobianco, Robert Peters, Jan Hilbrands, Daniel Laby, Heidi Martin, Jacqueline Rodena, Annette Bade, Airaj Fasiuddin, Blair Spencer, Justin Smith, Mei Mellott, Troy Kieser.

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

IMPORTANCE: The Intermittent Exotropia Questionnaire (IXTQ) is a patient, proxy, and parental report of quality of life specific to children with intermittent exotropia. We refine the IXTQ using Rasch analysis to improve reliability and validity. OBSERVATION: Rasch analysis was performed on responses of 575 patients with intermittent exotropia enrolled from May 15, 2008, through July 24, 2013, and their parents from each of the 4 IXTQ health-related quality-of-life questionnaires (child 5 through 7 years of age and child 8 through 17 years of age, proxy, and parent questionnaires). Questionnaire performance and structure were confirmed in a separate cohort of 379 patients with intermittent exotropia. One item was removed from the 12-item child and proxy questionnaires, and response options in the 8- to 17-year-old child IXTQ and proxy IXTQ were combined into 3 response options for both questionnaires. Targeting was relatively poor for the child and proxy questionnaires. For the parent questionnaire, 3 subscales (psychosocial, function, and surgery) were evident. One item was removed from the psychosocial subscale. Resulting subscales had appropriate targeting. CONCLUSIONS AND RELEVANCE: The Rasch-revised IXTQ may be a useful instrument for determining how intermittent exotropia affects health-related quality of life of children with intermittent exotropia and their parents, particularly for cohort studies.

Original languageEnglish
Pages (from-to)461-465
Number of pages5
JournalJAMA Ophthalmology
Volume133
Issue number4
DOIs
StatePublished - 1 Apr 2015

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