Evaluation of human placental lactogen (HPL) levels in anencephaly

J. Moshirpur, J. McCarrick, A. Bernett, J. Allerhand

Research output: Contribution to journalArticlepeer-review


Of the various hormonal and enzymatic tests that have been proposed for the assessment of fetal well-being, the determination of maternal estrogen levels in blood and/or urine and the placental hormone HPL have gained general acceptance. In anencephaly previous investigators have demonstrated that consistently low estrogen concentrations were a sign of the anomaly. However, a few cases have been reported in which urinary estrogen levels were in the low normal range. HPL concentration has been reported either as normal or low. Two cases of anencephaly are described in which low HPL levels were a major indicator of the abnormality.

Original languageEnglish
Pages (from-to)98-102
Number of pages5
JournalMount Sinai Journal of Medicine
Issue number1
StatePublished - 1978
Externally publishedYes


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