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Ethanol induction of CYP2A5: Permissive role for CYP2E1
Yongke Lu
, Jian Zhuge
, Defeng Wu
, Arthur I. Cederbaum
Icahn School of Medicine at Mount Sinai
Friedman Brain Institute
Graduate School of Biomedical Sciences
Pharmacological Sciences
Research output
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Contribution to journal
›
Article
›
peer-review
43
Scopus citations
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Keyphrases
Cytochrome P450 2E1 (CYP2E1)
100%
CYP2A5
100%
Ethanol Induction
100%
Ethanol
60%
Knock-in Mouse Model
53%
Wild Mice
20%
Hepatocarcinogen
13%
Liver
6%
Nicotine
6%
Immunohistochemical Staining
6%
Cellular Stress
6%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
6%
Reactive Oxygen Species
6%
Cadmium
6%
Stress Damage
6%
Xenobiotics
6%
Hepatic Damage
6%
Oxygen Activation
6%
Pharmacology, Toxicology and Pharmaceutical Science
CYP2E1
100%
Cytochrome P450 2A5
100%
Ethanol
100%
Knockout Mouse
26%
Messenger RNA
13%
Reactive Oxygen Metabolite
6%
Liver Injury
6%
Wild Type Mouse
6%
Transcription Factor Nrf2
6%
Nicotine
6%