Estimation of body hydration in dialysis patients using a calf bioimpedance method

Fansan Zhu, Li Liu, Peter Kotanko, Nathan W. Levin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Accurate estimation of normal hydration (dry weight) in hemodialysis (HD) patients is an important factor affecting patient mortality. Bioimpedance spectroscopy (BIS) has been used to measure extracellular (Re) and intracellular resistance (Ri) with a calf method (cBIS). An algorithm based on a fluid dynamic (FD) model has been developed to estimate change in intradialytic fluid volume in the calf during HD. We hypothesize that the flattening curve of change in Re and reaching the normal range of resistivity are the criteria to determine normal hydration state. The aim of this study was to evaluate whether the model and algorithm can be used in the clinic. 32 stable HD patients (19m/13f, age 55.8±15 yrs, height (H) 1.68±0.99 m and post-HD weight 71.9±15.3 kg) were studied with cBIS during HD treatments. To achieve dry weight, post HD weight were gradually reduced according to the criteria. Pre- and post-HD weight were reduced by mean of 1.36 kg and 1.15 kg respectively. The systolic blood pressure (SBP) decreased significantly (122.5± 22, vs. 114.3±21 mmHg, p<0.05). In conclusion, the FD model and algorithm has been applied successfully in dialysis patients.

Original languageEnglish
Title of host publication2010 International Conference on Biomedical Engineering and Computer Science, ICBECS 2010
DOIs
StatePublished - 2010
Externally publishedYes
Event2010 International Conference on Biomedical Engineering and Computer Science, ICBECS 2010 - Wuhan, China
Duration: 23 Apr 201025 Apr 2010

Publication series

Name2010 International Conference on Biomedical Engineering and Computer Science, ICBECS 2010

Conference

Conference2010 International Conference on Biomedical Engineering and Computer Science, ICBECS 2010
Country/TerritoryChina
CityWuhan
Period23/04/1025/04/10

Keywords

  • Body hydration
  • Calf bioimpedance
  • Component
  • Dry weight
  • Hemodialysis

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