Essential Characteristics of Pharmacogenomics Study Publications

Caroline F. Thorn; Michelle Whirl-Carrillo; Houda Hachad; Julie A. Johnson; Ellen M. McDonagh; Mark J. Ratain; Mary V. Relling; Stuart A. Scott; Russ B. Altman; Teri E. Klein

doi:10.1002/cpt.1279

Essential Characteristics of Pharmacogenomics Study Publications

Caroline F. Thorn
, Michelle Whirl-Carrillo
, Houda Hachad
, Julie A. Johnson
, Ellen M. McDonagh
, Mark J. Ratain
, Mary V. Relling
, Stuart A. Scott
, Russ B. Altman
, Teri E. Klein

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Pharmacogenomics (PGx) can be seen as a model for biomedical studies: it includes all disease areas of interest and spans in vitro studies to clinical trials, while focusing on the relationships between genes and drugs and the resulting phenotypes. This review will examine different characteristics of PGx study publications and provide examples of excellence in framing PGx questions and reporting their resulting data in a way that maximizes the knowledge that can be built on them.

Original language	English
Pages (from-to)	86-91
Number of pages	6
Journal	Clinical Pharmacology and Therapeutics
Volume	105
Issue number	1
DOIs	https://doi.org/10.1002/cpt.1279
State	Published - Jan 2019

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10.1002/cpt.1279

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abstract = "Pharmacogenomics (PGx) can be seen as a model for biomedical studies: it includes all disease areas of interest and spans in vitro studies to clinical trials, while focusing on the relationships between genes and drugs and the resulting phenotypes. This review will examine different characteristics of PGx study publications and provide examples of excellence in framing PGx questions and reporting their resulting data in a way that maximizes the knowledge that can be built on them.",

author = "Thorn, \{Caroline F.\} and Michelle Whirl-Carrillo and Houda Hachad and Johnson, \{Julie A.\} and McDonagh, \{Ellen M.\} and Ratain, \{Mark J.\} and Relling, \{Mary V.\} and Scott, \{Stuart A.\} and Altman, \{Russ B.\} and Klein, \{Teri E.\}",

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AU - Thorn, Caroline F.

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AU - Hachad, Houda

AU - Johnson, Julie A.

AU - McDonagh, Ellen M.

AU - Ratain, Mark J.

AU - Relling, Mary V.

AU - Scott, Stuart A.

AU - Altman, Russ B.

AU - Klein, Teri E.

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Essential Characteristics of Pharmacogenomics Study Publications

Abstract

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