Esophageal metastasis to the iris effectively palliated using stereotactic body radiation therapy and adjuvant intravitreal chemotherapy: Case report and literature review

Sughosh Dhakal, Gareth M.C. Lema, David A. Diloreto, Alan W. Katz

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

We report a case of isolated iris metastasis from esophageal adenocarcinoma that was successfully managed with local application of stereotactic body radiation therapy (SBRT) and adjunctive intravitreal therapy. A 53-year-old man with locally advanced esophageal adenocarcinoma achieved a complete clinical and radiographic response after surgery and chemotherapy. Four months later, he developed headache and decreased vision and was diagnosed with metastasis to the iris by slit-lamp examination. The decrease in vision was secondary to cystoid macular edema. The metastatic tumor and the patient's symptoms resolved after treatment with SBRT and intravitreal injections of bevacizumab and triamcinolone. We conclude that SBRT combined with intravitreal chemotherapy is an effective and well-tolerated palliative treatment for metastasis of esophageal adenocarcinoma to the iris.

Original languageEnglish
Pages (from-to)639-643
Number of pages5
JournalCase Reports in Oncology
Volume5
Issue number3
DOIs
StatePublished - Sep 2012
Externally publishedYes

Keywords

  • Bevacizumab
  • Esophageal carcinoma
  • Intravitreal injection
  • Iris metastasis
  • Stereotactic body radiation therapy

Fingerprint

Dive into the research topics of 'Esophageal metastasis to the iris effectively palliated using stereotactic body radiation therapy and adjuvant intravitreal chemotherapy: Case report and literature review'. Together they form a unique fingerprint.

Cite this