Escaping Negative Selection: ILC You in the Gut

Adam M. Farkas; Ivaylo I. Ivanov

doi:10.1016/j.immuni.2015.07.006

Escaping Negative Selection: ILC You in the Gut

Adam M. Farkas
, Ivaylo I. Ivanov

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4 Tcells in a form of extrathymic negative selection. How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4⁺ Tcells in a form of extrathymic negative selection.

Original language	English
Pages (from-to)	12-14
Number of pages	3
Journal	Immunity
Volume	43
Issue number	1
DOIs	https://doi.org/10.1016/j.immuni.2015.07.006
State	Published - 21 Jul 2015
Externally published	Yes

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title = "Escaping Negative Selection: ILC You in the Gut",

abstract = "How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4 Tcells in a form of extrathymic negative selection. How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4+ Tcells in a form of extrathymic negative selection.",

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N2 - How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4 Tcells in a form of extrathymic negative selection. How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4+ Tcells in a form of extrathymic negative selection.

AB - How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4 Tcells in a form of extrathymic negative selection. How commensal-specific Tcells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth etal. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4+ Tcells in a form of extrathymic negative selection.

UR - https://www.scopus.com/pages/publications/84937719200

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Escaping Negative Selection: ILC You in the Gut

Abstract

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