Abstract
Over the past year, the range of research related to erythroid cell-specific transcription has expanded beyond isolation of its transcriptional players to studies that address more complex yet still fundamental questions: first, whether these factors form part of a larger protein-protein structure; second, how factor interactions with DNA affect the surrounding chromatin configuration; third, how this affects the mechanism of gene switching within the β-like globin cluster; and finally, how these regulators are themselves transcriptionally controlled.
Original language | English |
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Pages (from-to) | 145-150 |
Number of pages | 6 |
Journal | Current Opinion in Hematology |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - 1998 |