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Erratum: Enhanced C/EBP binding to G·T mismatches facilitates fixation of CpG mutations in cancer and adult stem cells (Cell Reports (2021) 35(10), (S2211124721005726), (10.1016/j.celrep.2021.109221))

  • Anna S. Ershova
  • , Irina A. Eliseeva
  • , Oleg S. Nikonov
  • , Alla D. Fedorova
  • , Ilya E. Vorontsov
  • , Dmitry Papatsenko
  • , Ivan V. Kulakovskiy

Research output: Contribution to journalComment/debate

Abstract

(Cell Reports 35, 109221-1–7.e1–e4; June 8, 2021) In the originally published version of this article, “mismatch repair” was improperly used in the results and the graphical abstract. In both cases, it should have been the generic “DNA repair.” Additionally, “base excision repair” should have been used instead of “co-transcriptional repair” in the results. The corrected sentences appear below and now with the article online. “Second, the DNA-bound protein could make the respective DNA region inaccessible to other cellular machinery; i.e., tight C/EBP binding could protect a spontaneously deaminated site from DNA repair. This scenario could be realized through increased protein affinity to certain mismatches, which has been reported for many transcription factors (Afek et al., 2020), although C/EBP-related proteins were not explored in this regard. We hypothesized that it is the enhanced C/EBP binding that protects sites with mismatches from base excision repair and allows fixation of the respective mutations at the replication stage.” The authors regret this error.

Original languageEnglish
Article number109365
JournalCell Reports
Volume36
Issue number2
DOIs
StatePublished - 13 Jul 2021

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