Abstract
(Cell 167, 1264–1280.e1–e18; November 17, 2016) In our paper, we reported that polyploid macrophages form by mitotic defects and that their formation requires the DNA damage response. It has come to our attention that during the preparation of Figure 2D, we inadvertently duplicated column 1 (depicting the nuclear area of wild-type untreated macrophage precursors) as column 5 (depicting the nuclear area of Myd88−/− macrophage precursors treated with FSL-1). Upon discovering this error, we returned to the raw data and found that the correct files for each experimental condition had been generated and stored on the computer but that a manual error had occurred upon import into the Spotfire program for data visualization. In Spotfire, each column of the graph is plotted from an individual data file representing the results of the imaging analysis of each experimental condition, and we had inadvertently used one of the data files twice. We have generated an accurate version of Figure 2D from the original data files, which is shown below. This error in no way affects the results of the paper or the interpretation of the data and we have carefully evaluated all the Spotfire analyses in the manuscript to ensure no other manual errors occurred. We apologize for any confusion or inconvenience this error may have caused.
| Original language | English |
|---|---|
| Pages (from-to) | 1325-1326 |
| Number of pages | 2 |
| Journal | Cell |
| Volume | 174 |
| Issue number | 5 |
| DOIs |
|
| State | Published - 23 Aug 2018 |