Erosive syphilitic gastritis: dark field and immunofluorescent diagnosis from biopsy specimen

D. B. Sachar, R. S. Klein, F. Swerdlow, E. Bottone, M. T. Khilnani, J. D. Waye, M. Wisniewski

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

A 42 yr old man with positive blood and spinal fluid findings for syphilis had clinical, radiological, gastroscopic, and histological evidence of a severe infiltrative and erosive gastritis involving the entire distal stomach. Gastric tissue obtained from gastroscopic biopsy contained numerous motile spirochetes on dark field microscopy, with strongly positive specific treponemal immunofluorescence. The abnormalities resolved after a course of penicillin therapy. This case shows the propensity of late secondary syphilis to produce mucosal lesions in the stomach.

Original languageEnglish
Pages (from-to)512-515
Number of pages4
JournalUnknown Journal
Volume80
Issue number4
DOIs
StatePublished - 1974

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