Epstein-Barr virus nuclear antigen 1: From immunologically invisible to a promising T cell target

Christian Münz

Research output: Contribution to journalReview articlepeer-review

62 Scopus citations

Abstract

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1)-the one EBV antigen that is expressed in all EBV-associated malignancies-has long been thought to go undetected by the cell-mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV-related cancers.

Original languageEnglish
Pages (from-to)1301-1304
Number of pages4
JournalJournal of Experimental Medicine
Volume199
Issue number10
DOIs
StatePublished - 17 May 2004
Externally publishedYes

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