Epoxyeicosatrienoic acid administration or soluble epoxide hydrolase inhibition attenuates renal fibrogenesis in obstructive nephropathy

Keyphrases

• Renal Fibrogenesis 100%
• Obstructive Nephropathy 100%
• Soluble Epoxide Hydrolase 100%
• Epoxyeicosatrienoic Acids 100%
• Unilateral Ureteral Obstruction 41%
• Fibrogenesis 25%
• Kidney 16%
• Chronic Kidney Disease 16%
• Antifibrotic 16%
• Macrophage Markers 16%
• Inflammation 8%
• Inflammatory Response 8%
• Macrophage Infiltration 8%
• M2 Macrophages 8%
• Biological Effects 8%
• Hydrolysis 8%
• Collagen Deposition 8%
• Neutrophil Infiltration 8%
• Acid Treatment 8%
• Renal Fibrosis 8%
• Tubulointerstitial 8%
• Renoprotective Effect 8%
• Anti-apoptotic 8%
• Additive Effect 8%
• Mechanistic Understanding 8%
• Potential Therapeutic Strategies 8%
• Fibrotic Diseases 8%
• No Additives 8%
• M1 Macrophages 8%
• Arachidonic Acid Cascade 8%
• Tubular Injury 8%
• Pathophysiological Roles 8%
• Fibroblast Activation 8%
• Induced Oxidative Stress 8%
• Kidney Disease Model 8%
• Renal Tubulointerstitial Fibrosis 8%
• Tubular Apoptosis 8%
• Dihydroxyeicosatrienoic Acid 8%
• Regioisomers 8%
• Renal Interstitial 8%
• Renal Tubulointerstitial Inflammation 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Kidney Disease 100%
• Epoxide Hydrolase 100%
• Epoxyicosatrienoic Acid 100%
• Ureter Obstruction 41%
• Inflammation 25%
• Chronic Kidney Failure 16%
• Antiapoptotic 8%
• Fibrosis 8%
• Anti-Inflammatory Drug 8%
• Cytokine 8%
• Arachidonic Acid 8%
• Kidney Fibrosis 8%
• Diseases 8%