Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale

Madhav C. Menon; Michael J. Ross

doi:10.1016/j.kint.2015.12.025

Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale

Madhav C. Menon
, Michael J. Ross

Research output: Contribution to journal › Comment/debate

28 Scopus citations

Abstract

Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

Original language	English
Pages (from-to)	263-266
Number of pages	4
Journal	Kidney International
Volume	89
Issue number	2
DOIs	https://doi.org/10.1016/j.kint.2015.12.025
State	Published - 1 Feb 2016

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title = "Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale",

abstract = "Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.",

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AU - Ross, Michael J.

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N2 - Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

AB - Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

UR - https://www.scopus.com/pages/publications/84964588064

U2 - 10.1016/j.kint.2015.12.025

DO - 10.1016/j.kint.2015.12.025

M3 - Comment/debate

C2 - 26806826

AN - SCOPUS:84964588064

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SP - 263

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JO - Kidney International

JF - Kidney International

IS - 2

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Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: A new twist on an old tale

Abstract

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