Epigenetics in the nervous system

Yan Jiang, Brett Langley, Farah D. Lubin, William Renthal, Marcelo A. Wood, Dag H. Yasui, Arvind Kumar, Eric J. Nestler, Schahram Akbarian, Andrea C. Beckel-Mitchener

Research output: Contribution to journalArticlepeer-review

180 Scopus citations


It is becoming increasingly clear that epigenetic modifications are critical factors in the regulation of gene expression. With regard to the nervous system, epigenetic alterations play a role in a diverse set of processes and have been implicated in a variety of disorders. Gaining a more complete understanding of the essential components and underlying mechanisms involved in epigenetic regulation could lead to novel treatments for a number of neurological and psychiatric conditions.

Original languageEnglish
Pages (from-to)11753-11759
Number of pages7
JournalJournal of Neuroscience
Issue number46
StatePublished - 12 Nov 2008
Externally publishedYes


  • Chromatin
  • DNA methylation
  • Epigenetics
  • Gene
  • Histone
  • Transcription


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