Epigenetic Mechanisms in Inflammation

Epigenetic modifications are triggered by environmental changes and play a critical role in how genes are expressed in response to stimuli. The common epigenetic processes include histone, DNA methylation, and regulatory factor methylation, acetylation, and the short non-coding RNAs appearance. Epigenetic modifications cause susceptibility to disease and are modified by environmental factors like nutrition, pollution, and infection. Despite the rising form of knowledge on gene expression that is affected by the environment, other than that a very little is known about the epigenetic processes involved in the regulation of inflammatory and anti-inflammatory genes. Herein, we provide the present update on the mechanism of epigenetics during inflammation.