Epigenetic basis of memory

Bisrat T. Woldemichael; Isabelle M. Mansuy

doi:10.1016/B978-0-12-809324-5.21116-4

Epigenetic basis of memory

Bisrat T. Woldemichael, Isabelle M. Mansuy

Icahn School of Medicine at Mount Sinai

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

The mechanisms that allow the acquisition of information and the formation of memory in the brain recruit several epigenetic mechanisms. These mechanisms primarily include the classical epigenetic marks: DNA methylation and histone posttranslational modifications. Rodent models have allowed the identification of the major marks involved and some of the processes that underlie their instatement and regulation. This chapter provides an overview of the most important research in the field and describes some of the discovered epigenetic processes in learning and memory.

Original language	English
Title of host publication	The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Publisher	Elsevier Science Ltd.
Pages	247-256
Number of pages	10
ISBN (Electronic)	9780128093245
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.21116-4
State	Published - 1 Jan 2016

Keywords

Brain
DNA methylation
Epigenetic mechanisms
Histone modifications
Learning
Memory formation
Memory persistence

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10.1016/B978-0-12-809324-5.21116-4

Cite this

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KW - Histone modifications

KW - Learning

KW - Memory formation

KW - Memory persistence

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Epigenetic basis of memory

Abstract

Keywords

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