Abstract
Renal cell carcinoma (RCC) accounts for 2–3% of all adult malignant neoplasms. The incidence of RCC is increasing globally, with rates varying bycountry, age, race, and sex. Risk factors the development of RCC include cigarette smoking, obesity, hypertension, and industrial chemical exposure. In contrast, the consumption of fruit, vegtables and alcohol is associated with a decreased risk of RCC. In a minority of cases, the development of RCC is tiedto hereditary syndromes. This chapter will discuss established and proposed risk factors for RCC. In addition, the available evidence and mechanisms associated with each risk factor will be reviewed.
Original language | English |
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Title of host publication | Diagnosis and Surgical Management of Renal Tumors |
Publisher | Springer International Publishing |
Pages | 1-11 |
Number of pages | 11 |
ISBN (Electronic) | 9783319923093 |
ISBN (Print) | 9783319923086 |
DOIs | |
State | Published - 1 Jan 2018 |
Externally published | Yes |
Keywords
- Epidemiology
- Genetics
- Hypertension
- Incidence
- Obesity
- Renal cell carcinoma
- Risk factors
- Smoking