Epidemiology and Risk Factors of Renal Cell Carcinoma

Alexa R. Meyer, Mohamad E. Allaf, Michael A. Gorin

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Renal cell carcinoma (RCC) accounts for 2–3% of all adult malignant neoplasms. The incidence of RCC is increasing globally, with rates varying bycountry, age, race, and sex. Risk factors the development of RCC include cigarette smoking, obesity, hypertension, and industrial chemical exposure. In contrast, the consumption of fruit, vegtables and alcohol is associated with a decreased risk of RCC. In a minority of cases, the development of RCC is tiedto hereditary syndromes. This chapter will discuss established and proposed risk factors for RCC. In addition, the available evidence and mechanisms associated with each risk factor will be reviewed.

Original languageEnglish
Title of host publicationDiagnosis and Surgical Management of Renal Tumors
PublisherSpringer International Publishing
Pages1-11
Number of pages11
ISBN (Electronic)9783319923093
ISBN (Print)9783319923086
DOIs
StatePublished - 1 Jan 2018
Externally publishedYes

Keywords

  • Epidemiology
  • Genetics
  • Hypertension
  • Incidence
  • Obesity
  • Renal cell carcinoma
  • Risk factors
  • Smoking

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