Epidemiological Studies of Reproductive Effects in Humans

S. H. Swan; L. J. Guillette; J. P. Myers; F. S. vom Saal

doi:10.1016/B978-008045405-4.00882-X

Epidemiological Studies of Reproductive Effects in Humans

S. H. Swan, L. J. Guillette, J. P. Myers, F. S. vom Saal

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Evidence of significant effects of endocrine disrupting chemicals on human health has grown considerably in recent years. However, this new science of endocrine disruption presents considerable challenges to epidemiology, challenges that make identification of such effects in humans slow and difficult. We suggest several steps to develop a more ‘environmentally sensitive epidemiology’ and illustrate these concepts using data from two recent studies. These studies used biomarkers of exposure to low environmental levels of two classes of endocrine disrupting chemicals (phthalates and several current use pesticides) and precise outcome measures in order to examine the impacts of these chemicals on male reproductive human health.

Original language	English
Title of host publication	Encyclopedia of Ecology, Five-Volume Set
Publisher	Elsevier
Pages	1383-1388
Number of pages	6
Volume	1-5
ISBN (Electronic)	9780080454054
DOIs	https://doi.org/10.1016/B978-008045405-4.00882-X
State	Published - 1 Jan 2008
Externally published	Yes

Keywords

Biomarkers
Endocrine disruption
Epidemiology
Pesticides
Phthalates
Reproduction
Semen quality

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10.1016/B978-008045405-4.00882-X

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abstract = "Evidence of significant effects of endocrine disrupting chemicals on human health has grown considerably in recent years. However, this new science of endocrine disruption presents considerable challenges to epidemiology, challenges that make identification of such effects in humans slow and difficult. We suggest several steps to develop a more {\textquoteleft}environmentally sensitive epidemiology{\textquoteright} and illustrate these concepts using data from two recent studies. These studies used biomarkers of exposure to low environmental levels of two classes of endocrine disrupting chemicals (phthalates and several current use pesticides) and precise outcome measures in order to examine the impacts of these chemicals on male reproductive human health.",

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AU - Swan, S. H.

AU - Guillette, L. J.

AU - Myers, J. P.

AU - vom Saal, F. S.

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Y1 - 2008/1/1

N2 - Evidence of significant effects of endocrine disrupting chemicals on human health has grown considerably in recent years. However, this new science of endocrine disruption presents considerable challenges to epidemiology, challenges that make identification of such effects in humans slow and difficult. We suggest several steps to develop a more ‘environmentally sensitive epidemiology’ and illustrate these concepts using data from two recent studies. These studies used biomarkers of exposure to low environmental levels of two classes of endocrine disrupting chemicals (phthalates and several current use pesticides) and precise outcome measures in order to examine the impacts of these chemicals on male reproductive human health.

AB - Evidence of significant effects of endocrine disrupting chemicals on human health has grown considerably in recent years. However, this new science of endocrine disruption presents considerable challenges to epidemiology, challenges that make identification of such effects in humans slow and difficult. We suggest several steps to develop a more ‘environmentally sensitive epidemiology’ and illustrate these concepts using data from two recent studies. These studies used biomarkers of exposure to low environmental levels of two classes of endocrine disrupting chemicals (phthalates and several current use pesticides) and precise outcome measures in order to examine the impacts of these chemicals on male reproductive human health.

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KW - Endocrine disruption

KW - Epidemiology

KW - Pesticides

KW - Phthalates

KW - Reproduction

KW - Semen quality

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VL - 1-5

SP - 1383

EP - 1388

BT - Encyclopedia of Ecology, Five-Volume Set

PB - Elsevier

ER -

Epidemiological Studies of Reproductive Effects in Humans

Abstract

Keywords

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