Epidémiologie et génétique des maladies inflammatoires du tube digestif.

Translated title of the contribution: Epidemiology and genetics of inflammatory bowel diseases

A. Cortot, C. Gower-Rousseau, J. F. Colombel

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Inflammatory bowel diseases (IBDs) have been reported throughout the world, but their frequency is highest in Northern Europe and the USA. The mean incidence of ulcerative colitis (UC) is 6/10(5) inhabitants, and that of Crohn's disease (CD) is 4/10(5) inhabitants. IBDs occur in young adults, especially Crohn's disease which reaches a peak of incidence between the ages of 20 and 30 years. Among possible factors influencing their incidence, only tobacco smoking has been shown to facilitate the acute episodes and relapses of CD and to diminish those of UC. The frequency of familial IBDs, which mainly affects first degree relatives, varies from 6.1 to 35.8%. A genetic component is present and probably more important for CD than for UC, although no genetic marker has yet been identified.

Translated title of the contributionEpidemiology and genetics of inflammatory bowel diseases
Original languageFrench
Pages (from-to)393-396
Number of pages4
JournalRevue du Praticien
Issue number5
StatePublished - 11 Feb 1991
Externally publishedYes


Dive into the research topics of 'Epidemiology and genetics of inflammatory bowel diseases'. Together they form a unique fingerprint.

Cite this