Enzyme patterns in young and old mouse kidneys

P. D. Wilson, L. M. Franks

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Alkaline phosphatase, acid phosphatase, beta-glucuronidase, glucose-6-phosphate dehydrogenase (G6PDH), lactate dehydrogenase (LDH), succinic de-hydrogenase (SDH), cytochrome oxidase, glucose-6- phosphatase and 5'-nucleotidase activities assayed in baby (2-10 day), 6, 18 and 30-month-old male and female mouse kidney homogenates exhibited a complex pattern of change. Alkaline phosphatase, G6PDH, glucose-6-phosphatase and 5'-nucleotidase activities varied with age but sex was a very important modifying factor. Simultaneous light and electron microscope histochemistry showed no change in enzyme localization with age.

Original languageEnglish
Pages (from-to)16-32
Number of pages17
JournalGerontology
Volume17
Issue number1
DOIs
StatePublished - 1971
Externally publishedYes

Keywords

  • Electronmicro-histochemistry
  • Enzyme activity
  • Enzyme histochemistry
  • Mouse kidney

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