Enzymatic incorporation of 5-bromo cytidylic acid into the terminal sequence of S-RNA

R. L. Soffer; S. Uretsky; L. Altwerger; G. Acs

doi:10.1016/0006-291X(66)90167-7

Enzymatic incorporation of 5-bromo cytidylic acid into the terminal sequence of S-RNA

R. L. Soffer, S. Uretsky, L. Altwerger, G. Acs

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Abstract

In connection with other studies on the metabolism of nucleotide analogs in mammalian tissue, we have examined the effect of incorporating 5-bromo CMP into the terminal sequence of S-RNA in place of CMP. The results reported in this communication demonstrate (1) that Br-CMP can be incorporated into the terminal sequence of S-RNA in place of CMP, and (2) that such S-RNA functions effectively in accepting amino acids and in transferring them into peptide linkage.

Original language	English
Pages (from-to)	376-380
Number of pages	5
Journal	Biochemical and Biophysical Research Communications
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/0006-291X(66)90167-7
State	Published - 12 Aug 1966
Externally published	Yes

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abstract = "In connection with other studies on the metabolism of nucleotide analogs in mammalian tissue, we have examined the effect of incorporating 5-bromo CMP into the terminal sequence of S-RNA in place of CMP. The results reported in this communication demonstrate (1) that Br-CMP can be incorporated into the terminal sequence of S-RNA in place of CMP, and (2) that such S-RNA functions effectively in accepting amino acids and in transferring them into peptide linkage.",

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AU - Soffer, R. L.

AU - Uretsky, S.

AU - Altwerger, L.

AU - Acs, G.

PY - 1966/8/12

Y1 - 1966/8/12

N2 - In connection with other studies on the metabolism of nucleotide analogs in mammalian tissue, we have examined the effect of incorporating 5-bromo CMP into the terminal sequence of S-RNA in place of CMP. The results reported in this communication demonstrate (1) that Br-CMP can be incorporated into the terminal sequence of S-RNA in place of CMP, and (2) that such S-RNA functions effectively in accepting amino acids and in transferring them into peptide linkage.

AB - In connection with other studies on the metabolism of nucleotide analogs in mammalian tissue, we have examined the effect of incorporating 5-bromo CMP into the terminal sequence of S-RNA in place of CMP. The results reported in this communication demonstrate (1) that Br-CMP can be incorporated into the terminal sequence of S-RNA in place of CMP, and (2) that such S-RNA functions effectively in accepting amino acids and in transferring them into peptide linkage.

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DO - 10.1016/0006-291X(66)90167-7

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AN - SCOPUS:0014013133

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JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 3

ER -

Enzymatic incorporation of 5-bromo cytidylic acid into the terminal sequence of S-RNA

Abstract

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