TY - CHAP
T1 - Environmental medical epigenetics
T2 - A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products
AU - Miller, Rachel L.
AU - Oh, Jessica
N1 - Publisher Copyright:
© 2021 Elsevier Inc. All rights reserved.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary sources. The chapter will review the latest findings delineating their roles in disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies demonstrating environmental epigenetic regulation will be stressed, as will the importance of specific time windows of exposure. In general, this review suggests that despite continuing expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of exposure on epigenetic regulation.
AB - This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary sources. The chapter will review the latest findings delineating their roles in disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies demonstrating environmental epigenetic regulation will be stressed, as will the importance of specific time windows of exposure. In general, this review suggests that despite continuing expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of exposure on epigenetic regulation.
KW - DNA methylation
KW - Environmental epigenetics
KW - Histone modification
UR - http://www.scopus.com/inward/record.url?scp=85128090265&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-823928-5.00034-7
DO - 10.1016/B978-0-12-823928-5.00034-7
M3 - Chapter
AN - SCOPUS:85128090265
SP - 51
EP - 79
BT - Medical Epigenetics
PB - Elsevier
ER -