Environmental Medical Epigenetics: A Review of Epigenetically Induced Medical Risks Generated From Exposures in our Air, Food, and Personal Products

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

This chapter will cover key concepts related to multiple common environmental exposures such as allergens, pollutants, chemicals, and dietary exposures, and the latest findings implicating them as underlying mechanisms for disease development or exacerbation via epigenetic processes. Recent animal models and human cohort studies addressing these exposures will be stressed, as will the importance of specific time windows of exposure. Epigenome-wide and gene-specific associations will be covered. Results suggest that despite the great expansion of this field in recent years, many fundamental questions and research gaps remain, particularly those related to understanding the mechanisms that cause chronic diseases and the importance of specific time periods of environmental exposure.

Original languageEnglish
Title of host publicationMedical Epigenetics
PublisherElsevier Inc.
Pages103-125
Number of pages23
ISBN (Electronic)9780128032404
ISBN (Print)9780128032398
DOIs
StatePublished - 1 Jul 2016
Externally publishedYes

Keywords

  • DNA methylation
  • Environmental epigenetics
  • Histone modification

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