TY - JOUR
T1 - Enterovirus-human rhinovirus as a leading cause of ards in a liver transplant recipient
AU - Yousefi, Meysam
AU - Nadji, Seyed Alireza
AU - Farzanegan, Behrooz
AU - Hashemian, Seyed Mohammad Reza
AU - Marjani, Majid
AU - Moniri, Afshin
AU - Javanmard, Pedram
AU - Tabarsi, Payam
N1 - Publisher Copyright:
© 2019 NRITLD, National Research Institute of Tuberculosis and Lung Disease, Iran.
PY - 2019
Y1 - 2019
N2 - A 35-year-old man with a prior history of liver transplantation 18 months ago was admitted to our Intensive Care Unit (ICU) with fever and worsening dyspnea and was diagnosed with severe pneumonia leading to Acute Respiratory Distress Syndrome (ARDS). He had a prolonged hospitalization and was treated with empiric broad spectrum intravenous antibiotics, oseltamivir, trimethoprim/sulfamethoxazole, and subsequently caspofungin and ganciclovir. Blood, nasopharyngeal, as well as Bronchoalveolar Lavage (BAL) culture and Polymerase Chain Reaction (PCR) were negative for all viral, bacterial, and fungal causes of pulmonary infection except Enterovirus-Human Rhinovirus (EV-HRV) that was positive with high titers on BAL and swab specimens. Consequently, the diagnosis of EV-HRV pneumonia complicated by ARDS was established. The patient gradually improved and was discharged from the hospital after 3 weeks. This report highlights EV-HRV as a cause of ARDS in immunocompromised adults.
AB - A 35-year-old man with a prior history of liver transplantation 18 months ago was admitted to our Intensive Care Unit (ICU) with fever and worsening dyspnea and was diagnosed with severe pneumonia leading to Acute Respiratory Distress Syndrome (ARDS). He had a prolonged hospitalization and was treated with empiric broad spectrum intravenous antibiotics, oseltamivir, trimethoprim/sulfamethoxazole, and subsequently caspofungin and ganciclovir. Blood, nasopharyngeal, as well as Bronchoalveolar Lavage (BAL) culture and Polymerase Chain Reaction (PCR) were negative for all viral, bacterial, and fungal causes of pulmonary infection except Enterovirus-Human Rhinovirus (EV-HRV) that was positive with high titers on BAL and swab specimens. Consequently, the diagnosis of EV-HRV pneumonia complicated by ARDS was established. The patient gradually improved and was discharged from the hospital after 3 weeks. This report highlights EV-HRV as a cause of ARDS in immunocompromised adults.
KW - Acute respiratory distress syndrome (ARDS)
KW - Enterovirus-Human Rhinovirus
KW - Immunosuppression
KW - Transplantation
UR - http://www.scopus.com/inward/record.url?scp=85078008505&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85078008505
SN - 1735-0344
VL - 18
SP - 169
EP - 172
JO - Tanaffos
JF - Tanaffos
IS - 2
ER -