Enhancing Opioid Bioactivity Predictions through Integration of Ligand-Based and Structure-Based Drug Discovery Strategies with Transfer and Deep Learning Techniques

Keyphrases

• Opioids 100%
• Deep Learning Methods 100%
• Drug pipeline 100%
• Ligand Structure 100%
• Structure-based Drug Discovery 100%
• Ligand-based 100%
• Transfer Learning Model 100%
• Bioactivity Prediction 100%
• Deep Learning Model 66%
• Opioid Receptors 33%
• Receptor Function 33%
• Drug Discovery 33%
• Bioactivity 33%
• Public Health 33%
• Chemical Probes 33%
• Opioid Receptor Subtypes 33%
• Artificial Intelligence 33%
• Training Samples 33%
• Performance Prediction 33%
• Opioid Drugs 33%
• Opioid Epidemic 33%
• Machine Learning System 33%
• Rapid Identification 33%
• Bioactivity Data 33%
• Novel Chemicals 33%
• Tool Pose 33%
• Transfer Learning 33%
• Immediate Action 33%
• Addiction Potential 33%
• Supervised Learning 33%
• Molecular Descriptors 33%
• Leveraging Knowledge 33%
• Robust Deep Learning 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Opiate Receptor 100%
• Drug Discovery 100%
• Receptor 50%
• Receptor Subtype 50%

Neuroscience

• Receptor 100%
• Receptor Subtype 50%