TY - JOUR
T1 - Enhanced detection of proximal right coronary artery stenosis with the additional analysis of right ventricular thallium-201 uptake in stress scintigrams
AU - Gutman, Jack
AU - Brachman, Michael
AU - Rozanski, Alan
AU - Maddahi, Jamshid
AU - Waxman, Alan
AU - Berman, Daniel S.
N1 - Funding Information:
From the Division of Cardiology, Department of Medicine, and the Department of Nuclear Medicine, Cedars-Sinai Medical Center, and the Departments of Medicine and Radiology, UCLA School of Medicine, Los Angeles, California . This study was supported in part by SCOR Grant 17651 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, and a grant-in-aid to Dr . Rozanski from the American Heart Association, Greater Los Angeles Affiliate, Los Angeles, California . Manuscript received June 15, 1982; revised manuscript received January 31, 1983, accepted February 2, 1983 .
PY - 1983/5/1
Y1 - 1983/5/1
N2 - The value of right ventricular thallium-201 analysis in detecting proximal right coronary artery stenosis in exercise myocardial scintigraphy was analyzed in 52 patients, 27 with and 25 without proximal right coronary artery stenosis. For the detection of proximal right coronary artery stenosis, the sensitivity and specificity of thallium scintigraphic analysis were 59 and 88% for a right ventricular abnormality, 67 and 68% for a left ventricular inferior wall abnormality, and 93 and 56% for an abnormality of either. When both right and left ventricular thallium images were abnormal, all 9 patients had proximal right coronary artery stenoses, and when both were normal, 26 of 28 patients had a normal proximal right coronary artery. The sensitivity and specificity of blood pool scintigraphic variables during exercise (right ventricular ejection fraction and left ventricular inferior wall motion) were not significantly different for detection of proximal right coronary artery stenosis. Thus, the additional analysis of the right ventricle on thallium-201 stress scintigrams can improve the detection of proximal right coronary artery stenosis. When both right ventricular and left ventricular thallium scintigrams are abnormal (or normal), the ability to predict the presence (or absence) of proximal right coronary artery stenosis is very high.
AB - The value of right ventricular thallium-201 analysis in detecting proximal right coronary artery stenosis in exercise myocardial scintigraphy was analyzed in 52 patients, 27 with and 25 without proximal right coronary artery stenosis. For the detection of proximal right coronary artery stenosis, the sensitivity and specificity of thallium scintigraphic analysis were 59 and 88% for a right ventricular abnormality, 67 and 68% for a left ventricular inferior wall abnormality, and 93 and 56% for an abnormality of either. When both right and left ventricular thallium images were abnormal, all 9 patients had proximal right coronary artery stenoses, and when both were normal, 26 of 28 patients had a normal proximal right coronary artery. The sensitivity and specificity of blood pool scintigraphic variables during exercise (right ventricular ejection fraction and left ventricular inferior wall motion) were not significantly different for detection of proximal right coronary artery stenosis. Thus, the additional analysis of the right ventricle on thallium-201 stress scintigrams can improve the detection of proximal right coronary artery stenosis. When both right ventricular and left ventricular thallium scintigrams are abnormal (or normal), the ability to predict the presence (or absence) of proximal right coronary artery stenosis is very high.
UR - http://www.scopus.com/inward/record.url?scp=0020537113&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(83)90295-3
DO - 10.1016/0002-9149(83)90295-3
M3 - Article
C2 - 6846153
AN - SCOPUS:0020537113
SN - 0002-9149
VL - 51
SP - 1256
EP - 1260
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 8
ER -