@inproceedings{aea135df196745a589d1b4f9c00b891e,
title = "Engineered cardiac tissues for in vitro assessment of contractile function and repair mechanisms",
abstract = "For efficiently assessing the potential for grafted cells to repair infarcted myocardium, a simplified surrogate heart muscle system would offer numerous advantages. Using neonatal rat cardiac myocytes in a collagen matrix, we created thin cylindrical engineered cardiac tissues (ECTs) that exhibit essential aspects of physiologic cardiac muscle function. Furthermore, a novel cryo-injured ECT model of myocardial infarction offers the potential for the longitudinal study of mechanisms of cell-based cardiac repair in vitro.",
author = "Kim, \{Do Eun\} and Lee, \{Eun Jung\} and Martens, \{Timothy P.\} and Rina Kara and Chaudhry, \{Hina W.\} and Silviu Itescu and Costa, \{Kevin D.\}",
year = "2006",
doi = "10.1109/IEMBS.2006.259753",
language = "English",
isbn = "1424400325",
series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
pages = "849--852",
booktitle = "28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06",
note = "28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 ; Conference date: 30-08-2006 Through 03-09-2006",
}