Endoscopic tracheoplasty segmental tracheal ring resection in a porcine model

Gary S. Schwartz, Syed Shahzad Razi, Scott J. Belsley, Deva Boone, Mohammed J. Latif, Cliff P. Connery, Robert S. Lebovics, Faiz Y. Bhora

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Endoscopic tracheoplasty is used for the relief of airway obstruction because of several benign conditions such as postintubation stenosis, inflammatory disorders such as Wegener granulomatosis, and benign neoplastic processes. Several endoscopic treatment modalities exist for these conditions, all with good initial results. However, recurrence is common and often requires frequent reinter- vention. Endoscopic segmental tracheal ring resection is a novel therapeutic approach that could potentially provide a durable solution. Endoscopic segmental tracheal ring resection was performed in 3 Yorkshire pigs under general anesthesia. A combination of bipolar cautery and sharp dissection was used to resect 25% to 33% of the circumference of a single tracheal ring. Technical success was achieved in all 3 animals with no intraoperative complications. Full-thickness excision, including the anterior perichondrium, was performed in 1 animal without violation of the pretracheal fascia, with no subcutaneous emphysema or clinically apparent pneumothorax. Average operative time was 31 minutes and estimated blood loss was minimal. Heart rate, oxygen saturation, and peak airway pressures were maintained within normal ranges during the procedure and for the 60-minute postoperative period. Histologic analysis of the resected specimen confirmed complete thickness excision of the segment of tracheal cartilage. Endoscopic tracheoplasty by segmental tracheal ring resection is a safe and feasible technique in a porcine model. Long-term durability could potentially outlast other endoscopic techniques for the treatment of bening tracheal stenosis. Survival studies in a porcine model of tracheal stenosis must be performed to assess the long-term outcomes of this approach.

Original languageEnglish
Pages (from-to)232-235
Number of pages4
JournalJournal of Bronchology and Interventional Pulmonology
Issue number3
StatePublished - Jul 2010
Externally publishedYes


  • Benign tracheal stenosis
  • Endoscopy
  • Tracheoplasty
  • Wegener granulomatosis


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