Endoscopic third ventriculostomy in patients with a diminished prepontine interval: Clinical article

Mark M. Souweidane, Peter F. Morgenstern, Sungkwon Kang, Apostolos John Tsiouris, Jonathan Roth

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27 Scopus citations


Object. Fenestration of the floor of the third ventricle is vital to the success of endoscopic third ventriculostomy (ETV) in treating patients with noncommunicating hydrocephalus. A generous prepontine interval (PPI) is generally accepted as one anatomical feature that may affect the safety and functionality of ETV. Whether a diminished PPI influences the safety or success of ETV, however, has not been adequately assessed. Methods. A review was conducted on the last 100 ETV procedures performed by the first author (M.M.S.). From archived preoperative MR imaging studies, the PPI was measured between the dorsum sellae and the basilar artery. For any patient with an interval of ≤ 1 mm, the technical and functional success of the procedure was recorded. Technical success was defined when a surgically created fenestration was accomplished without patient morbidity. Functional success was defined as the patient not needing any additional CSF diversionary procedure within 3 months after ETV. Results. In the entire cohort, the PPI ranged from 0 to 9.5 mm (mean 3.2 mm). There were 15 procedures performed in patients with a PPI of ≤ 1 mm. In all 15 procedures, a fenestration of the tuber cinereum was accomplished without vascular injury or patient morbidity. The ETV was successful in 11 patients (73.3%). All 4 failures occurred in children who had surgery during infancy (mean age 11 months). Conclusions. Patients with an obliterated or reduced PPI can safely undergo ETV. The functional success rate appears equivalent to historical controls. Most failures in this series may be attributed to other patient characteristics, namely young age at the time of ETV.

Original languageEnglish
Pages (from-to)250-254
Number of pages5
JournalJournal of Neurosurgery: Pediatrics
Issue number3
StatePublished - Mar 2010
Externally publishedYes


  • Dorsum sellae
  • Endoscopic third ventriculostomy
  • Prepontine interval


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