Endoscopic Response Reduces the Risk of Subsequent Pouchitis in Patients with Crohn’s Disease Like Pouch Inflammation

Maia Kayal, Hannah Posner, Darwin Jimenez, Justin Huang, Marla C. Dubinsky, Jean Frederic Colombel

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: The aim of this study was to report the frequency and impact of endoscopic response and remission on the risk of subsequent pouchitis in patients with Crohn’s disease like pouch inflammation (CDLPI) on therapy. Methods: This was a single center, retrospective study of patients >18 years with CDLPI on therapy. Results: Among 110 included patients with CDLPI in clinical remission, endoscopic remission was not significantly associated with a reduced risk of subsequent pouchitis when compared to endoscopic response. Conclusions: Endoscopic response, not remission, is sufficient to reduce the risk of subsequent pouchitis in patients with CDLPI.

Original languageEnglish
Article number10.14309/ajg.0000000000003055
JournalAmerican Journal of Gastroenterology
DOIs
StateAccepted/In press - 2024

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