Endophthalmitis associated with glaucoma drainage implants

Carlos A. Medina, Michelle R. Butler, Avnish A. Deobhakta, Michael R. Banitt, Thomas A. Albini, William E. Smiddy, Audina M. Berrocal, Steven J. Gedde, Harry W. Flynn

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


BACKGROUND AND OBJECTIVE: To identify the clinical features, organisms, and treatment outcomes in patients with endophthalmitis associated with glaucoma drainage implants. PATIENTS AND METHODS: A retrospective noncomparative case series. RESULTS: Of the 13 patients, exposure occurred in eight eyes, including exposure of the tube in four eyes, exposure of the patch graft in three eyes, and exposure of the plate in one eye. In the remaining five eyes, either recent implant placement or conjunctival revision occurred. The most common organism was Staphylococcus epidermidis (five eyes). Intravitreal antibiotics were administered in all eyes, with the exception of one eye (primary evisceration). Removal of the implant was performed in six eyes and evisceration or enucleation was performed in three eyes. Median pre-infection visual acuity was 20/80 (range: 20/30 to hand motion). Visual acuity at last follow-up was no light perception (five eyes), light perception (two eyes), hand motion (one eye), and better than or equal to 20/200 (five eyes). CONCLUSION: Clinical features associated with endophthalmitis include implant exposure and a history of recent surgery. Staphylococcus epidermidis was the most common isolate. Although removal of the implant was performed in many patients, successful treatment was accomplished in some patients without removal. Visual outcomes were generally poor.

Original languageEnglish
Pages (from-to)563-569
Number of pages7
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number6
StatePublished - Jun 2016
Externally publishedYes


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