TY - JOUR
T1 - Endocrine and metabolic issues in the management of the chronically critically ill patient
AU - Mechanick, Jeffrey I.
AU - Brett, Elise M.
PY - 2002
Y1 - 2002
N2 - The metabolic syndrome of chronic critical illness (CCI) consists of multisystem organ dysfunction resulting from the initial acute injury and chronic immune-neuroendocrine axis activation, adult kwashiorkor-like malnutrition, and prolonged immobilization with suppression of the PTH-vitamin D axis and hyperresorptive metabolic bone disease. CCI patients can also present unique challenges in the management of diabetes mellitus, thyroid and adrenal diseases, electrolyte abnormalities and hypogonadism.
AB - The metabolic syndrome of chronic critical illness (CCI) consists of multisystem organ dysfunction resulting from the initial acute injury and chronic immune-neuroendocrine axis activation, adult kwashiorkor-like malnutrition, and prolonged immobilization with suppression of the PTH-vitamin D axis and hyperresorptive metabolic bone disease. CCI patients can also present unique challenges in the management of diabetes mellitus, thyroid and adrenal diseases, electrolyte abnormalities and hypogonadism.
UR - https://www.scopus.com/pages/publications/0036314267
U2 - 10.1016/S0749-0704(02)00005-2
DO - 10.1016/S0749-0704(02)00005-2
M3 - Review article
C2 - 12140916
AN - SCOPUS:0036314267
SN - 0749-0704
VL - 18
SP - 619
EP - 641
JO - Critical Care Clinics
JF - Critical Care Clinics
IS - 3
ER -