Endocrine and metabolic issues in the management of the chronically critically ill patient

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Abstract

The metabolic syndrome of chronic critical illness (CCI) consists of multisystem organ dysfunction resulting from the initial acute injury and chronic immune-neuroendocrine axis activation, adult kwashiorkor-like malnutrition, and prolonged immobilization with suppression of the PTH-vitamin D axis and hyperresorptive metabolic bone disease. CCI patients can also present unique challenges in the management of diabetes mellitus, thyroid and adrenal diseases, electrolyte abnormalities and hypogonadism.

Original languageEnglish
Pages (from-to)619-641
Number of pages23
JournalCritical Care Clinics
Volume18
Issue number3
DOIs
StatePublished - 2002

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