1 Scopus citations

Abstract

Covalent inhibitors can obtain optimal selectivity and extended residence time. In this issue of Cell Chemical Biology, Shraga et al. (2019) take a comprehensive computational and experimental approach to modulate the JNK-Jun pathway through design of MKK7 covalent inhibitors. This study highlights a promising and emerging strategy for therapeutic discovery.

Original languageEnglish
Pages (from-to)6-8
Number of pages3
JournalCell Chemical Biology
Volume26
Issue number1
DOIs
StatePublished - 17 Jan 2019

Fingerprint

Dive into the research topics of 'Encounter and React: Computer-Guided Design of Covalent Inhibitors'. Together they form a unique fingerprint.

Cite this